K. Joe et al., SYNTHESES AND CHARACTERIZATIONS OF LACTAM CYCLOPHANES - ATTEMPTED SYNTHESIS OF A LACTAM CATENANE USING HYDROGEN-BONDS, Bulletin of the Korean Chemical Society, 16(11), 1995, pp. 1079-1084
New cylophanes having multilactam linkages were synthesized and charac
terized. One-pot coupling reaction of 2,6-pyridinedicarbonyl dichlorid
e and a diamine gave a tetralactam, a hexalactam, and a octalactam in
good yields. The TLC behaviour, the molecular symmetry shown by H-1 NM
R spectrum, and the fragmentation patterns shown by FAB mass spectrum
of the octalactam support its monocyclic structure.