Bereavement is a major risk factor for physical illness, grief, depres
sion, and anxiety. In contrast to recent tendencies in the psychiatric
literature to equate grief and depression, we propose that a careful
discrimination between the two must be made for diagnostic, therapeuti
c, and investigative purposes. We report the results of a longitudinal
study of a frequent but neglected event, miscarriage early in pregnan
cy, to make this point. Clinical criteria for differentiating grief an
d depressive reactions were developed based on phenomenological criter
ia and theoretical considerations. We hypothesized that the detrimenta
l psychological and physical consequences occur only when the miscarri
age was not mourned and resulted in a depressive reaction, but not in
a grief reaction. In a controlled, representative study, 125 consecuti
ve women were assessed shortly after their miscarriage (before the 20t
h week of gestation) and 6 months (N = 94) and 12 months (N = 90) late
r. Assessments included standardized questionnaires for life events, d
epression, physical complaints, anxiety, and a specific, multidimensio
nal grief scale (Munich Grief Scale) that we had developed previously.
Immediately after the miscarriage, the average anxiety and depression
scores were elevated when compared with 80 pregnant and 125 age-match
ed community controls. Twenty percent of the patients who had miscarri
ed showed a grief reaction, 12% showed a depressive reaction, and 20%
responded with a combined depressive and grief reaction. The remaining
women (48%) reported no changes in their emotional reactions. As pred
icted, longer-lasting psychological, social, and health status changes
followed the initial depressive, but not the grief reactions. Depress
ive reactions were predicted by a history of previous depression, a la
ck of social resources, and an ambivalent attitude to the lost fetus.
The grief measures were reliable and made it possible to discriminate
between grief and depression.