TARGETING OF COLLOIDS TO LYMPH-NODES - INFLUENCE OF LYMPHATIC PHYSIOLOGY AND COLLOIDAL CHARACTERISTICS

The lymphatic uptake of colloids, whether lipid or non-lipid in nature , is determined by the physiology of the lymphatic system, and the phy sicochemical characteristics of the colloid in question, The fate of t he colloid is also determined by the route of administration, with the subcutaneous route generally considered to be most appropriate for ta rgeting to the regional lymph nodes. With greater understanding of the se factors, it will be possible to target the lymph nodes more effecti vely.