R. Ahner et al., FETAL FIBRONECTIN AS A SELECTION CRITERION FOR INDUCTION OF TERM LABOR, American journal of obstetrics and gynecology, 173(5), 1995, pp. 1513-1517
OBJECTIVE: We examined whether the presence of fetal fibronectin in ce
rvicovaginal secretions can be used as a selection criterion for induc
tion of labor at term. STUDY DESIGN: Cervicovaginal secretions of 64 w
omen who were scheduled for induction of labor were examined for fetal
fibronectin and divided into group A (positive for fibronectin) and g
roup B (negative for fibronectin). Both groups were examined for Bisho
p score, the number of prostaglandin tablets administered, and the int
erval between induction of labor and delivery. RESULTS: In group A the
interval between induction of labor and delivery was significantly sh
orter (p < 0.0001) than in group B. The number of prostaglandin tablet
s administered to group A was likewise significantly lower (p < 0.0001
). Unsuccessful induction of labor only occurred in women with fibrone
ctin-negative cervicovaginal secretions. CONCLUSION: The assessment of
the fibronectin content of cervicovaginal secretions constitutes a vi
able instrument in the decision-making process preceding induction of
labor.