NMR-TOMOGRAPHY OF THE BRAIN IN PARKINSONS -DISEASE

Because cerebral atrophy and white substance of the cerebral hemispher es became typical findings at NMR tomography of the brain in Parkinson 's disease, the authors initiated a study to quantify the observed def ects. A combination of neurological, neuropsychological and NMR-tomogr aphy methods with addition of formalized scales has been utilized. The severity of cerebral atrophy and that of neurological and psychic dis orders were related. Internal atrophy was more frequently observed in older patients, the external one was more characteristic for patients with systemic atherosclerosis. Multiple focal lesions of the white sub stance were encounted in associated arterial hypertension and was pres ent in all the patients with distinct cerebral atrophy. Diffuse lesion s of the white substance (leukareosis) showed no relationship to any o f the factors studied.