CHEMICAL SYNTHESIS AND COMPLEXING BEHAVIOR OF BRANCHED CYCLODEXTRINS COMPOSED OF AN AMYLOSE AND A BETA-CYCLODEXTRIN RESIDUE

The synthesis of a new class of branched cyclodextrins is presented. I n these compounds an amylose residue with a degree of polymerization ( DP) of 30 is attached to the C6 position of a beta-cyclodextrin molecu le via an alkyl spacer. Hence, these hosts are composed of a combinati on of two different components linked covalently, both having individu al properties. The complexing behaviour was investigated by circular d ichroism (CD) spectroscopy. The CD spectra indicate that the inclusion geometry of some guest compounds into the beta-cyclodextrin cavity is influenced by the amylose side chain. However, an additional complexa tion of these guests inside the amylose helix was not observed.