AGE-SPECIFIC SEROPREVALENCE OF HEPATITIS-B VIRUS-INFECTION

In this study, we have tried to determine the age-specific seroprevale nce of hepatitis B virus (HBV) infection and to make some conclusions about the mode of transmission and vaccination strategy which should b e chosen in Turkey. Eight hundred and one patients between the ages of six months and 60 years of age were included in this study. According to the HBV serologic markers, (HBsAg, Anti-HBc and Anti-HBs), HBsAg p ositivity and HBV exposure rates were 6.5% and 32.8%, respectively. HB sAg positivity was 6.6% under one year of age. The highest rate of HBs Ag positivity was in the 6-10 year age-group (p<0.05). The prevalence of total hepatitis B virus seropositivity increased with age (p<0.05). The HBV exposure rate was higher in males than in females (p<0.05). I t was concluded that HBV infection is an important infection in Turkey and is acquired very early in life. A mass hepatitis B vaccination st rategy should thus be chosen in Turkey.