Fp. Roldan et al., COMBINED HEPATOCELLULAR-CHOLANGIOCARCINOM A WITH METASTASES AND HYPERCALCEMIA, Revista espanola de enfermedades digestivas, 87(10), 1995, pp. 743-747
The combined hepatocellular-cholagiocarcinoma (CHCC) is a very uncommo
n neoplasm, its diagnosis is difficult and its course is usually very
rapid. We report the case of a patient with CHCC type II or transition
al tumor, which shows two cellular types in certain zones. Our patient
had tumoral hypercalcemia as well, which was very difficult to contro
l. There was a metastatic spread with cholangiolar features almost fro
m the begining, that made impossible any sort of therapy. It seems tha
t disemination followed lymphatic pathways.