ISOLATION OF ENDOTHELIN-A RECEPTOR FROM BOVINE LUNGS

Authors
HICK S GODOVACZIMMERMANN J
Citation
S. Hick et J. Godovaczimmermann, ISOLATION OF ENDOTHELIN-A RECEPTOR FROM BOVINE LUNGS, Journal of cardiovascular pharmacology, 26, 1995, pp. 276-278
Citations number
10
Categorie Soggetti
Cardiac & Cardiovascular System","Respiratory System","Pharmacology & Pharmacy
Journal title
Journal of cardiovascular pharmacology → ACNP
ISSN journal
01602446
Volume
26
Year of publication
1995
Supplement
3
Pages
276 - 278
Database
ISI
SICI code
0160-2446(1995)26:<276:IOERFB>2.0.ZU;2-H
Abstract
We isolated endothelin receptor A (ET(A)) from bovine lungs in a singl e-step purification procedure using antibodies raised against syntheti c peptides that correspond to extra- and intracellular domains of the rat bradykinin receptor. Two receptor species of 55 and 35 kDa were is olated and subjected to N-terminal microsequencing. The difference bet ween the observed and expected molecular weight species suggests that bovine ET(A) receptor is glycosylated.