We investigated the influence of different sterilization techniques on
the degree of oxidation of UHMWPE. Oxidation effects were documented
by infrared spectroscopy. The UHMWPE was sterilized with the aid of ga
mma radiation (2.5 Mrad) in air, gamma radiation in argon, ethylene ox
ide and autoclaving. Non-sterilized UHMWPE served as control material.
The results showed significant differences for the various sterilizat
ion techniques employed. The highest degree of oxidation was seen afte
r autoclaving, but gamma radiation was also associated with a signific
ant degree of oxidation. Using gamma radiation in argon, the degree of
oxidation was significantly reduced. Following sterilization with eth
ylene oxide, no oxidation was to be found. In view of these facts, UHM
WPE should be sterilized only with ethylene oxide or with gamma radiat
ion in argon.