HEMOLYTIC-ANEMIA PROVOKED BY RECOMBINANT ALPHA-INTERFERON

Authors
TAKASE K NAKANO T HAMADA M SHIRAKI K OOHASHI Y KIHIRA T TAMEDA Y
Citation
K. Takase et al., HEMOLYTIC-ANEMIA PROVOKED BY RECOMBINANT ALPHA-INTERFERON, Journal of gastroenterology, 30(6), 1995, pp. 795-797
Citations number
NO
Categorie Soggetti
Gastroenterology & Hepatology
Journal title
Journal of gastroenterology → ACNP
ISSN journal
09441174
Volume
30
Issue
6
Year of publication
1995
Pages
795 - 797
Database
ISI
SICI code
0944-1174(1995)30:6<795:HPBRA>2.0.ZU;2-X
Abstract
A 30-year-old female with chronic hepatitis C treated with recombinant alpha-interferon developed serious hemolytic anemia after receiving 1 0 million units a day for 4 weeks. The results of Coombs' tests were n egative before and after interferon therapy. The hemolytic anemia grad ually improved after the withdrawal of recombinant alpha-interferon an d the administration of methyl-prednisolone. The clinical course sugge sted that the recombinant alpha-interferon had provoked the hemolytic anemia.