PSYCHO-NEURO-IMMUNE-ENDOCRINE SYSTEM BEHAVIOR LN MECHANICAL TRAUMA

Mechanical energy is an etiological factor of traumatisms which, in th e human being, can produce a local pathology as well as localized syst emic acute inflammation as in the case of polytraumatized patients. Ac ute local inflammation is a process that occurs with vasoconstriction, vasodilatation, exudation, cellular infiltration, coagulation, fibrin olysis and proliferation. These phases of the inflammation can be expr essed by the endothelium, although they make up part of a localizing a nd successive response of the nervous, immune and endocrine systems. I n the polytraumatized patients, the ischemia-revascularization, the sy stemic inflammatory response syndrome, the disseminated intravascular coagulation and the anabolism of the convalescence period would in tur n represent the consecutive systemic expression of the nervous, immune and endocrine systems. If injury by mechanic energy produces a consec utive response of the nervous, immune and endocrine systems in the hum an being, it could be considered that these systems represent the succ essive expression of functions such as motility, digestion and prolife ration which, in turn, are common components of other vital cycles exi sting in nature. Essentially, the final function that each system succ essively expresses would be a type of response that has persisted in p hysiological and pathological situations due to its adaptive effectivi ty, in this special case, to the mechanical energy.