BACKGROUND: The goal of this study was to determine if the outcome of
antireflux surgery can be improved by: (1) conducting a careful preope
rative workup to characterize gastroesophageal reflux disease (GERD) i
n the individual patient; and (2) tailoring the operation to the resul
ts of the preoperative function tests. PATIENTS AND METHODS: Sixty-eig
ht patients had operations for GERD by minimally invasive techniques.
RESULTS: A Rossetti fundoplication was performed in 22 patients. Sixty
-eight percent became asymptomatic. Twenty-seven percent developed dys
phagia or gas bloat. Thirty-five patients had a Nissen fundoplication.
Ninety-one percent are asymptomatic. Eleven patients with severe abno
rmalities of esophageal peristalsis underwent a Guarner fundoplication
with relief of symptoms in 82% of patients. No patients in the Nissen
or Guarner group developed postoperative persistent dysphagia or gas
bloat. A pyloromyotomy was performed in 3 patients because of severe d
elayed gastric emptying. CONCLUSIONS: Minimally invasive surgery for G
ERD gives good-to-excellent results even in patients with abnormal eso
phageal body function, provided that the operation is tailored to the
individual patient based on the results of the preoperative function t
ests.