SUBRETINAL TUMOR IN A PATIENT WITH A LIMITED FORM OF WEGENERS GRANULOMATOSIS

In 1939 F. Wegener published a report concerning a peculiar febrile sy ndrome with necrotizing inflammation of the upper respiratory tract, f ocal glomerulonephritis and systemic angiitis (Wegener 1939), Clinical ly Wegener's granulomatosis can be divided into a limited and a genera lized form, We describe a patient presenting with unilateral ocular sy mptoms suspicious of a neoplasm, one episode of angina pectoris and ge neral malaise without any clinical signs of upper respiratory tract in volvement, Before Wegener's granulomatosis was diagnosed by a positive titre of antineutrophil cytoplasmic antibodies and open lung biopsy, immunoscintigraphy for malignant melanoma showed a false positive resu lt. Systemic treatment with corticosteroids and cyclophosphamide resul ted in an improvement of the ocular symptoms within weeks.