AN UNUSUAL TYPE OF FAMILIAL LIPODYSTROPHY

Authors
JOHANSEN K RASMUSSEN MH KJEMS LL ASTRUP A
Citation
K. Johansen et al., AN UNUSUAL TYPE OF FAMILIAL LIPODYSTROPHY, The Journal of clinical endocrinology and metabolism, 80(12), 1995, pp. 3442-3446
Citations number
39
Categorie Soggetti
Endocrynology & Metabolism
Journal title
The Journal of clinical endocrinology and metabolism → ACNP
ISSN journal
0021972X
Volume
80
Issue
12
Year of publication
1995
Pages
3442 - 3446
Database
ISI
SICI code
0021-972X(1995)80:12<3442:AUTOFL>2.0.ZU;2-3
Abstract
A mother and her daughter with a novel type of familial partial lipody strophy were studied. Both had atrophy of fat in the face, chest, and upper and lower limbs and abdominal obesity caused by intraabdominal f at accumulation. The mother had severe insulin resistance and impaired glucose tolerance, whereas the daughter had normal glucose tolerance and normal insulin sensitivity. Both had metabolic rates about 30% abo ve normal levels, but normal thyroid function and plasma lipids.