EFFECTS OF LONG-TERM MONOTHERAPY WITH DRU GS FROM THE MAIN 4 GROUPS OF ANTIHYPERTENSIVE AGENTS ON LIFE QUALITY OF PATIENTS WITH MILD AND MODERATE ARTERIAL-HYPERTENSION - MULTICENTER TRIAL CAPTOPRIL AND LIFE QUALITY

Authors
METELITS VI DUDA SG OSTROVSKAYA TP FILATOVA NP MUKHAMEDZHANOVA GF VYGODIN VA SIEGRIST J BROER M
Citation
Vi. Metelits et al., EFFECTS OF LONG-TERM MONOTHERAPY WITH DRU GS FROM THE MAIN 4 GROUPS OF ANTIHYPERTENSIVE AGENTS ON LIFE QUALITY OF PATIENTS WITH MILD AND MODERATE ARTERIAL-HYPERTENSION - MULTICENTER TRIAL CAPTOPRIL AND LIFE QUALITY, Terapevticeskij arhiv, 67(9), 1995, pp. 45-50
Citations number
NO
Categorie Soggetti
Medicine, General & Internal
Journal title
Terapevticeskij arhiv → ACNP
ISSN journal
00403660
Volume
67
Issue
9
Year of publication
1995
Pages
45 - 50
Database
ISI
SICI code
0040-3660(1995)67:9<45:EOLMWD>2.0.ZU;2-Z
Abstract
A multicenter, controlled, open, randomized trial of antihypertensive rind lift quality (LQ) effects of monotherapy with captopril vs propan olol, hydrochlorothiazide and nifedipine included 345 males aged 35-60 years with mild and moderate hypertension. The results of 8-month tre atment provided the conclusions: the drugs were much alike by antihype rtensive efficacy. LQ parameters proved more beneficial in the group o n captopril than those on nifedipine and propanolol, hydrochlorothiazi de failed to improve life quality, captopril is an effective and safe antihypertensive drug superior to the drugs of 3 other antihypertensiv e drug groups by positively affecting LQ.