Recycling the contents of a continuous fermenter through a stripping c
olumn is proposed as a means of reducing product inhibition and loweri
ng the cost of fuel ethanol production. A 2-L fermenter and 10-cm pack
ed column were continuously operated for 150 days without contaminatio
n. Some fouling of the packing with attached yeast cells was observed
which partially blocked the column. Cell yield was lower than in a sim
ple continuous fermenter. Complete conversion of 200 g/L glucose feed
and 90% conversion of 600 g/L glucose feed were achieved. Data were an
alyzed by computerized process simulation. Cost analysis indicated tha
t, with heat recovery to reduce heating and cooling costs, the continu
ous fermentor/stripper is possibly a lower-cost alternative to convent
ional fermentation and distillation.