SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF 7-BETA-[N-(ARYLMETHYLOXYIMINO) ACETAMIDO]CEPHALOSPORANIC ACID-DERIVATIVES

Authors
MACCHIA M MENCHINI E ORLANDINI E ROSSELLO A BROCCALI G VISCONTI M
Citation
M. Macchia et al., SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF 7-BETA-[N-(ARYLMETHYLOXYIMINO) ACETAMIDO]CEPHALOSPORANIC ACID-DERIVATIVES, Il Farmaco, 50(10), 1995, pp. 713-718
Citations number
20
Categorie Soggetti
Pharmacology & Pharmacy
Journal title
Il Farmaco → ACNP
ISSN journal
0014827X
Volume
50
Issue
10
Year of publication
1995
Pages
713 - 718
Database
ISI
SICI code
0014-827X(1995)50:10<713:SAAAO7>2.0.ZU;2-Q
Abstract
Some cephalosporanic acid derivatives substituted on the C(7) amino ni trogen with (arylmethyloxyimino) acetyl moieties were synthesized and tested in vitro for their antimicrobial activity against Gram positive and Gram negative bacteria. The new compounds showed a modest activit y directed only against Gram positive microorganisms.