PHARMACOKINETICS OF TAMOXIFEN IN PREMENOPAUSAL AND POSTMENOPAUSAL WOMEN WITH BREAST-CANCER

Authors
LIEN EA ANKER G UELAND PM
Citation
Ea. Lien et al., PHARMACOKINETICS OF TAMOXIFEN IN PREMENOPAUSAL AND POSTMENOPAUSAL WOMEN WITH BREAST-CANCER, Journal of steroid biochemistry and molecular biology, 55(2), 1995, pp. 229-231
Citations number
19
Categorie Soggetti
Biology,"Endocrynology & Metabolism
Journal title
Journal of steroid biochemistry and molecular biology → ACNP
ISSN journal
09600760
Volume
55
Issue
2
Year of publication
1995
Pages
229 - 231
Database
ISI
SICI code
0960-0760(1995)55:2<229:POTIPA>2.0.ZU;2-E
Abstract
We measured the serum levels of tamoxifen and 5 of its metabolites in serum from 7 premenopausal and 9 postmenopausal women during the first 56 days of treatment. The serum levels of N-desdimethyltamoxifen were higher in postmenopausal women compared to premenopausal women (P< 0. 02). A similar trend was observed for N-desmethyltamoxifen (P=0.06).