EFFECT OF DIETARY-INTAKE ON URINARY OXALATE EXCRETION IN CALCIUM RENAL STONE FORMERS

Objective To investigate the influence of dietary intake on urinary ox alate excretion in calcium renal-stone formers. Patients and methods D ietary intake was monitored by using the dietary-record method in 60 i diopathic stone formers, The patients collected their urine for 24 h a t home and their urinary oxalate excretion rate was determined, The re lationship between the daily intake of various nutrients and urinary o xalate excretion was examined by both monovariate and multivariate ana lyses, Results By monovariate analysis. the intake of carbohydrate, to tal protein and fat were significantly correlated with urinary oxalate excretion, but the intake of calcium and body surface area were not. In addition, the intake of total protein was highly correlated with th at of fat, By multivariate analysis, the intake of carbohydrate and fa t were significantly related to urinary oxalate excretion, and the int ake of calcium was inversely correlated with urinary oxalate excretion , but the intake of total protein showed no significant correlation Co nclusion The intake of carbohydrate and fat was positively and the int ake of calcium was inversely correlated with urinary oxalate excretion in stone formers and, taken together, these findings suggested that f at plays an important role in urinary oxalate excretion and that prote in has a minimal effect.