Jg. Noble et al., URETHRAL SPHINCTER VOLUMES IN WOMEN WITH OBSTRUCTED VOIDING AND ABNORMAL SPHINCTER ELECTROMYOGRAPHIC ACTIVITY, British Journal of Urology, 76(6), 1995, pp. 741-746
Objective To investigate the role of transrectal ultrasonography (TRUS
) of the female urethral sphincter and to compare sphincter volumes in
controls and women With obstructed voiding associated with abnormal m
yotonic-like electromyographic (EMG) activity in the urethral sphincte
r. Patients and methods Fourteen women patients (mean age 29+/-3.2 yea
rs) with symptoms of urinary outlet obstruction underwent videocystome
trography (VCMG), urethral sphincter EMG and TRUS. Their sphincter vol
umes were compared with those obtained from 20 age-matched control pat
ients with other urodynamic diagnoses or normal urodynamics. Results I
n every patient the urethral sphincter was identified as an ovoid, hyp
oechoic structure distal to the bladder outlet. The mean volume of the
sphincter in those patients with abnormal EMG activity (3.05+/-0.23 c
m(3)) was significantly greater than that in the control group (1.30+/
-0.09 cm(3); P<0.001). Conclusion TRUS provided a useful method of ima
ging the urethral sphincter in women. The results suggest that there w
as an increase in the volume of the urethral sphincter in females with
obstructed voiding, providing collateral evidence that the abnormal E
MG activity is a significant factor in the pathophysiology of the diso
rder.