Enteritis necroticans is a necrotizing process manifesting as segmenta
l gangrene of the bowel, triggered by Clostridium perfringens toxins u
nder specific dietary conditions. It is a rare disease in developed co
untries and is probably underdiagnosed. A case of enteritis necrotican
s presenting with midgut necrosis with sepsis and hemolysis is reporte
d herein. Bacteriologic culture of blood and peritoneal content reveal
ed C perfringens. Dietary history, including the ingestion of meat tog
ether with sweet potatoes, should increase clinical suspicion of enter
itis necroticans. Early recognition and timely surgical intervention a
re required for successful treatment. Clinicians are encouraged to be
aware of this clinically fulminant yet rarely recognized surgical enti
ty.