In this paper, we develop mathematical machinery for verifying that a
broad class of general state space Markov chains reacts smoothly to ce
rtain types of perturbations in the underlying transition structure. O
ur main result provides conditions under which the stationary probabil
ity measure of an ergodic Harris-recurrent Markov chain is differentia
ble in a certain strong sense. The approach is based on likelihood rat
io 'change-of-measure' arguments, and leads directly to a 'likelihood
ratio gradient estimator' that can be computed numerically.