STUDY ON THE THERMAL-STABILITY OF A CHIRAL STATIONARY-PHASE COATED ONCAPILLARIES FOR GC

A chiral stationary phase prepared by bonding L-valine-t-butylamide to XE-60 has been coated on glass and metal capillaries, The performance s of the chiral glass and metal columns were equivalent to those of co mmercial fused silica capillary columns, The thermal stability of the glass column was examined up to 280 degrees C. It was found that no ap preciable change in separation factor (alpha value) was observed up to 230 degrees C. The alpha values gradually decreased between 240 and 2 60 degrees C, and enantiomer separation was no longer achieved at 280 degrees C, It was concluded that the allowable upper limit temperature of the chiral stationary phase is between 230 and 240 degrees C in th e isothermal mode, and ca 260 degrees C in temperature-programmed mode .