SERUM GASTRIN-LEVELS IN PATIENTS WITH COLORECTAL-CANCER AND ADENOMATOUS POLYPS - A PROSPECTIVE-STUDY

Authors
MIHAS AA MALIAKKAL RJ SHUEKE M ACHORD JL
Citation
Aa. Mihas et al., SERUM GASTRIN-LEVELS IN PATIENTS WITH COLORECTAL-CANCER AND ADENOMATOUS POLYPS - A PROSPECTIVE-STUDY, Research communications in molecular pathology and pharmacology, 90(2), 1995, pp. 301-304
Citations number
11
Categorie Soggetti
Pharmacology & Pharmacy",Pathology,Biology
Journal title
Research communications in molecular pathology and pharmacology → ACNP
ISSN journal
10780297
Volume
90
Issue
2
Year of publication
1995
Pages
301 - 304
Database
ISI
SICI code
1078-0297(1995)90:2<301:SGIPWC>2.0.ZU;2-8
Abstract
Serum gastrin levels were measured by radioimmunoassay in 62 patients with colorectal neoplasms (40 with adenomatous polyps and 22 with canc er) and 40 controls. Fasting serum gastrin in both the polyp (73.93 +/ - 6.5 pg/ml) and the cancer (99 +/- 19.7 pg/ml) groups was significant ly higher than those of the control group (42.65 +/- 2.2 pg/ml). These findings suggest that hypergastrinemia may be an etiologic factor in colorectal neoplasia.