SYNTHETIC STUDIES TOWARDS TAXOL ANALOGS - CHEMOSELECTIVE CLEAVAGE OF C-5 CINNAMOYL GROUP IN TAXANE GROUP OF DITERPENOIDS WITH HYDROXYLAMINE

Citation
Y. Bathini et al., SYNTHETIC STUDIES TOWARDS TAXOL ANALOGS - CHEMOSELECTIVE CLEAVAGE OF C-5 CINNAMOYL GROUP IN TAXANE GROUP OF DITERPENOIDS WITH HYDROXYLAMINE, Synthetic communications, 24(11), 1994, pp. 1513-1517
Citations number
13
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
ISSN journal
00397911
Volume
24
Issue
11
Year of publication
1994
Pages
1513 - 1517
Database
ISI
SICI code
0039-7911(1994)24:11<1513:SSTTA->2.0.ZU;2-K
Abstract
Taxane group of diterpenoids 2 and 3 which possess cinnamoyl moiety at C-5 position underwent selective cleavage to C-5 hydroxy compounds 4 and 5 on treatment with hydroxylamine. The resulting compounds were ch aracterised based on their spectral data.