SEPARATION OF ENANTIOMERS OF DRUGS BY CAPILLARY ELECTROPHORESIS .1. GAMMA-CYCLODEXTRIN AS CHIRAL SOLVATING AGENT

Authors
KOPPENHOEFER B EPPERLEIN U CHRISTIAN B JI YB CHEN YY LIN BC
Citation
B. Koppenhoefer et al., SEPARATION OF ENANTIOMERS OF DRUGS BY CAPILLARY ELECTROPHORESIS .1. GAMMA-CYCLODEXTRIN AS CHIRAL SOLVATING AGENT, Journal of chromatography, 717(1-2), 1995, pp. 181-190
Citations number
19
Categorie Soggetti
Chemistry Analytical","Biochemical Research Methods
Journal title
Journal of chromatography → ACNP
Volume
717
Issue
1-2
Year of publication
1995
Pages
181 - 190
Database
ISI
SICI code
Abstract
Enantiomer separation was studied for a set of 57 chiral drugs. With g amma-cyclodextrin as chiral solvating agent in capillary zone electrop horesis, seven enantiomeric pairs could be separated without recoursin g to an optimization procedure. Possible interaction mechanisms betwee n selector and selectand molecules are briefly discussed.