TARDIVE-DYSKINESIA IN NONWESTERN COUNTRIES - A REVIEW

Citation
Ak. Pandurangi et Ya. Aderibigbe, TARDIVE-DYSKINESIA IN NONWESTERN COUNTRIES - A REVIEW, European archives of psychiatry and clinical neuroscience, 246(1), 1995, pp. 47-52
Citations number
43
Categorie Soggetti
Psychiatry,Neurosciences
ISSN journal
09401334
Volume
246
Issue
1
Year of publication
1995
Pages
47 - 52
Database
ISI
SICI code
0940-1334(1995)246:1<47:TINC-A>2.0.ZU;2-Y
Abstract
Tardive dyskinesia (TD) is a well-described adverse effect of treatmen t with neuroleptics. Studies from non-western countries are sparse and those that exist are not well publicized. We analyzed prevalence data on TD, published in English or French, and carried out in countries i n Africa and Asia through December 1993. The estimated prevalence of T D among African subjects was 24% and among Asian subjects 17.20%. Both rates are in the middle range when compared with the western prevalen ce rates of 10-50%. Long-term hospitalization and older age were risk factors associated with TD. Female gender did not emerge as a risk fac tor. Also, several Asian studies showed that subjects with TD were tak ing lower doses of neuroleptics than subjects without TD. Prospective and controlled cross-cultural studies of TD are recommended for better understanding of associated risk factors and primary prevention.