Ak. Pandurangi et Ya. Aderibigbe, TARDIVE-DYSKINESIA IN NONWESTERN COUNTRIES - A REVIEW, European archives of psychiatry and clinical neuroscience, 246(1), 1995, pp. 47-52
Tardive dyskinesia (TD) is a well-described adverse effect of treatmen
t with neuroleptics. Studies from non-western countries are sparse and
those that exist are not well publicized. We analyzed prevalence data
on TD, published in English or French, and carried out in countries i
n Africa and Asia through December 1993. The estimated prevalence of T
D among African subjects was 24% and among Asian subjects 17.20%. Both
rates are in the middle range when compared with the western prevalen
ce rates of 10-50%. Long-term hospitalization and older age were risk
factors associated with TD. Female gender did not emerge as a risk fac
tor. Also, several Asian studies showed that subjects with TD were tak
ing lower doses of neuroleptics than subjects without TD. Prospective
and controlled cross-cultural studies of TD are recommended for better
understanding of associated risk factors and primary prevention.