Autoaggregation was frequently encountered among intestinal lactobacil
li isolated from weaned pigs. The aggregation mechanism was shown to b
e mediated by the production of a proteinaceous aggregation-promoting
factor in two strains of Lactobacillus reuteri. A 32 kDa aggregation-p
romoting protein was detected in these strains by cross-reaction with
rabbit polyclonal antibodies for Aggregation-Promoting Factor produced
by the human isolate Lact. plantarum 4B2. Coaggregation reactions of
Lact. reuteri strains with pathogenic and non-pathogenic Escherichia c
oli were detected.