LOCALIZATION OF ANGIOTENSIN-IV BINDING-SITES TO MOTOR AND SENSORY NEURONS IN THE SHEEP SPINAL-CORD AND HINDBRAIN

Citation
I. Moeller et al., LOCALIZATION OF ANGIOTENSIN-IV BINDING-SITES TO MOTOR AND SENSORY NEURONS IN THE SHEEP SPINAL-CORD AND HINDBRAIN, Brain research, 701(1-2), 1995, pp. 301-306
Citations number
15
Categorie Soggetti
Neurosciences
Journal title
ISSN journal
00068993
Volume
701
Issue
1-2
Year of publication
1995
Pages
301 - 306
Database
ISI
SICI code
0006-8993(1995)701:1-2<301:LOABTM>2.0.ZU;2-H
Abstract
In the sheep spinal cord, a high density of [I-125]angiotensin IV bind ing sites was localized to the perikaryon and processes of all somatic motor neurons, the autonomic motor neurons in the lateral hems of tho racic and lumbar segments and all dorsal root ganglia, but was low in lamina II of all dorsal horns. At supraspinal levels, [I-125]angiotens in IV binding was abundant in numerous motor associated regions, with weaker binding observed in the sensory regions. This wide distribution pattern suggests an important role for the binding site in the centra l nervous system.