RELATIONS AMONG AGING, ANTIOXIDANT STATUS, AND CATARACT

Light and oxygen are necessary for the function of the eye. However, w hen present in excess or in uncontrolled circumstances, they appear to be related, probably causally, to the development of cataract. Compro mises of function of the lens and retina with aging are exacerbated by depleted or diminished primary antioxidant reserves, antioxidant enzy me capabilities, and diminished secondary defenses such as proteases. Smoking appears to provide an additional oxidative challenge associate d with depletion of antioxidants as well as with enhanced risk for cat aract formation. Poor education and lower socioeconomic status are ass ociated with poorer nutriture and are also significantly related to in creased risk for these debilities. Optimizing nutriture, including die ts rich in fruit and vegetables, may provide the least costly and most practicable means to delay cataract.