NUCLEOSIDE 3'-METHYLPHOSPHONOFLUORIDATES AND NUCLEOSIDE 3'-METHYLFLUORIDOPHOSPHONOTHIOATES - NEW CONVENIENT INTERMEDIATES IN LARGE-SCALE SYNTHESIS OF DINUCLEOSIDE-(3',5')-METHYLPHOSPHONATES
W. Dabkowski et al., NUCLEOSIDE 3'-METHYLPHOSPHONOFLUORIDATES AND NUCLEOSIDE 3'-METHYLFLUORIDOPHOSPHONOTHIOATES - NEW CONVENIENT INTERMEDIATES IN LARGE-SCALE SYNTHESIS OF DINUCLEOSIDE-(3',5')-METHYLPHOSPHONATES, Tetrahedron letters, 36(50), 1995, pp. 9223-9224
Nucleoside 3'-methylphosphonofluoridates 3 and nucleoside 3'-methylflu
oridophosphonothioates 5 for the first time are used directly in the s
ynthesis of dinucleosidemethylphosphonates and methylphosphonothioates
. The fluoridophosphonothioates 5 were separated into pure diastereome
rs.