TRIFLUOROMETHYLALKENES IN CYCLOADDITION REACTIONS

Authors
BONNETDELPON D BEGUE JP LEQUEUX T OUREVITCH M
Citation
D. Bonnetdelpon et al., TRIFLUOROMETHYLALKENES IN CYCLOADDITION REACTIONS, Tetrahedron, 52(1), 1996, pp. 59-70
Citations number
49
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
52
Issue
1
Year of publication
1996
Pages
59 - 70
Database
ISI
SICI code
0040-4020(1996)52:1<59:TICR>2.0.ZU;2-8
Abstract
CF3-Substituted alkenes have been described to be good partners in Die ls-Alder reactions with the Danishefsky's diene and in 1,3-dipolar cyc loadditions with nitrones and non-stabilized azomethine ylides. The in fluence of the CF3-group on both the activation of the double bond and the stereochemistry of the cycloaddition has been evaluated. New CF3- substituted mono- and polycyclic compounds 4 and 7, highly functionali zed isoxazolidines 18, 19, 22 and 23 and pyrrolidines 12, 13 and 16 ha ve been prepared.