CF3-Substituted alkenes have been described to be good partners in Die
ls-Alder reactions with the Danishefsky's diene and in 1,3-dipolar cyc
loadditions with nitrones and non-stabilized azomethine ylides. The in
fluence of the CF3-group on both the activation of the double bond and
the stereochemistry of the cycloaddition has been evaluated. New CF3-
substituted mono- and polycyclic compounds 4 and 7, highly functionali
zed isoxazolidines 18, 19, 22 and 23 and pyrrolidines 12, 13 and 16 ha
ve been prepared.