Nine progressive supranuclear palsy (PSP) patients were studied with c
omputerized tomography (CT) and magnetic resonance (MR) in order to de
termine the efficacy of each in detecting atrophy of the brainstem. Th
ree additional PSP patients were evaluated with MRT for quantitative (
electronic) measurements of the colliculi, pens and midbrain tegmentum
, Both CT and MRI were equally effective in demonstrating midbrain atr
ophy, The MR was able to utilize the sagittal view to visualize thinni
ng of the collicular (quadrigeminal) plate, a useful sign in PSP, Atro
phy of the thinned collicular plate is more pronounced in the superior
colliculus, one of the most common sites of pathology in PSP, The MR
is able to make quantitative measurements of the degree of atrophy of
the colliculi, pens and midbrain tegmentum.