PERIPHERAL PRIMITIVE NEUROECTODERMAL TUMOR AFTER ALLOGENEIC BONE-MARROW TRANSPLANTATION

We report a case of peripheral primitive neuroectodermal tumour (PNET) in a 36-year-old man who 10 years earlier received an allogeneic bone marrow transplantation (BMT) for a non-Hodgkin's lymphoma. Immunohist ochemistry proved definitive elimination of a relapse of the original disease and confirmed the diagnosis of PNET. The role of total body ir radiation pre-BMT in the genesis of this secondary tumour is discussed . The importance of registering secondary malignant solid tumours afte r BMT is bone emphasized. To our knowledge, an Ewing family tumour fol lowing BMT has not previously been reported.