CONGENITAL STREPTOCOCCAL TOXIC SHOCK SYNDROME WITH ABSENCE OF ANTIBODIES AGAINST STREPTOCOCCAL PYROGENIC EXOTOXINS

Congenital infection with group A beta-hemolytic streptococcus was com plicated by toxic shock syndrome in a neonate. We hypothesize that the severity of the clinical syndrome was related to the streptococcal py rogenic exotoxin in the absence of corresponding antibodies. The outco me may have been favorably influenced by the antibodies to streptococc al pyrogenic exotoxin present in the immunoglobulins given as treatmen t.