DEPROTONATION-ALKYLATION OF ALKYL CYANIDES UNDER SONOCHEMICAL CONDITIONS

Citation
J. Berlan et al., DEPROTONATION-ALKYLATION OF ALKYL CYANIDES UNDER SONOCHEMICAL CONDITIONS, Synthetic communications, 24(9), 1994, pp. 1253-1260
Citations number
13
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
ISSN journal
00397911
Volume
24
Issue
9
Year of publication
1994
Pages
1253 - 1260
Database
ISI
SICI code
0039-7911(1994)24:9<1253:DOACUS>2.0.ZU;2-P
Abstract
Deprotonation-alkylation of n-alkyl cyanides can be readily effected b y an alkyl halide in the presence of sodium in a one pot procedure. Yi elds are generally better than in the usual methods, and the overall r eaction conditions have important advantages in terms of ease and simp licity compatible with preparative scale-up.