SEROLOGICAL PRECURSORS OF CANCER - MALIGNANT-MELANOMA, BASAL AND SQUAMOUS-CELL SKIN-CANCER, AND PREDIAGNOSTIC LEVELS OF RETINOL, BETA-CAROTENE, LYCOPENE, ALPHA-TOCOPHEROL, AND SELENIUM
Ra. Breslow et al., SEROLOGICAL PRECURSORS OF CANCER - MALIGNANT-MELANOMA, BASAL AND SQUAMOUS-CELL SKIN-CANCER, AND PREDIAGNOSTIC LEVELS OF RETINOL, BETA-CAROTENE, LYCOPENE, ALPHA-TOCOPHEROL, AND SELENIUM, Cancer epidemiology, biomarkers & prevention, 4(8), 1995, pp. 837-842
To determine the association between prediagnostic serum levels of ret
inol, beta-carotene, lycopene, alpha-tocopherol, and selenium and the
subsequent risk of malignant melanoma, and basal and squamous cell ski
n cancer, a nested case-control study among residents of Washington Co
unty, MD, was performed. Cases with melanoma (n = 30), basal cell (n =
32), and squamous cell (n = 37) skin cancer who were admitted to hosp
ital for treatment or biopsy of metastatic lesions were each matched b
y age, sex, and race with two controls. There were no significant asso
ciations between serum micronutrient levels and the risk of subsequent
skin cancer.