MODELING SELECTIVE ACTIVATION OF SMALL MYELINATED NERVE-FIBERS USING A MONOPOLAR POINT ELECTRODE

Citation
Njm. Rijkhoff et al., MODELING SELECTIVE ACTIVATION OF SMALL MYELINATED NERVE-FIBERS USING A MONOPOLAR POINT ELECTRODE, Medical & biological engineering & computing, 33(6), 1995, pp. 762-768
Citations number
25
Categorie Soggetti
Engineering, Biomedical","Computer Science Interdisciplinary Applications
ISSN journal
01400118
Volume
33
Issue
6
Year of publication
1995
Pages
762 - 768
Database
ISI
SICI code
0140-0118(1995)33:6<762:MSAOSM>2.0.ZU;2-0
Abstract
The aim of this study is to investigate theoretically the possibility for activation of small myelinated nerve fibres without activating lar ger ones when stimulating a nerve fibre bundle using a monopolar point electrode. Therefore, the Sensitivity of excitation and blocking thre shold currents of nerve fibres to fibre diameter, electrode-fibre dist ance and pulse duration has been simulated by a computer model. A simp le infinite, homogeneous volume conductor and a cathodal point source were used in combination with a model representing the electrical prop erties of a myelinated nerve fibre. The results show that selective ac tivation of small myelinated fibres may be possible in a region at som e distance from the electrode.