THE IMPORTANCE OF FLUENCE RATE IN PHOTODYNAMIC THERAPY - IS THERE A PARALLEL WITH IONIZING-RADIATION DOSE-RATE EFFECTS

Authors
VEENHUIZEN RB STEWART FA
Citation
Rb. Veenhuizen et Fa. Stewart, THE IMPORTANCE OF FLUENCE RATE IN PHOTODYNAMIC THERAPY - IS THERE A PARALLEL WITH IONIZING-RADIATION DOSE-RATE EFFECTS, Radiotherapy and oncology, 37(2), 1995, pp. 131-135
Citations number
25
Categorie Soggetti
Oncology,"Radiology,Nuclear Medicine & Medical Imaging
Journal title
Radiotherapy and oncology → ACNP
ISSN journal
01678140
Volume
37
Issue
2
Year of publication
1995
Pages
131 - 135
Database
ISI
SICI code
0167-8140(1995)37:2<131:TIOFRI>2.0.ZU;2-H
Abstract
Several similarities can be found between dose-rate effects in radioth erapy and fluence-rate effects in photodynamic therapy (PDT). At low d ose rates repair of sublethal damage can occur, whereas at high dose r ates oxygen depletion can decrease the effects of both therapies. The available literature for fluence-rate effects in PDT is discussed here in relation to therapeutic implications.