Uh. Ross et al., LOCALIZATION OF ACTIVE OTOSCLEROTIC FOCI BY TYMPANO-COCHLEAR SCINTIGRAPHY (TCS) USING CORRELATIVE IMAGING, Journal of Laryngology and Otology, 109(11), 1995, pp. 1051-1056
High-resolution, tympano-cochlear scintigraphy (TCS) is a useful tool
for visualizing changes in labyrinthine bone metabolism in active otos
clerosis in vivo. But until now, the activity patterns have mostly bee
n rather imprecisely ascribed to the labyrinthine structures; more exa
ctly by means of high resolution CT (HR-CT). Experimental studies on T
CS using a human temporal bone model revealed that correlative imaging
of X-ray photographs and the scintigrams or superimposition with mask
s of the temporal bone drawn from the X-rays can facilitate the locali
zation of small foci of about 0.5-1 mm. Clinical applications of the v
isualization technique, combining functional with structural images, c
onfirmed the benefit of this method, improving the accuracy in detecti
on and localization of focal activity enrichment of the petrous bone i
n cases of active otosclerosis by means of TCS.