Recurrent pericardial effusion or tamponade can complicate malignant d
isease. The medical approach with pharmacologic agents has a high recu
rrence rate, Balloon pericardiotomy (BP) may provide a less invasive a
lternative to surgery, We pet-formed BP in ten high-risk patients with
malignant pericardial tamponade (MPT), BP was performed,vith aseptic
technique under fluoroscopic and echocardiographic guidance, We used a
percutaneous subxiphoid approach. A 20- to 25-mm-wide and 4-cm-long b
alloon was introduced over a stiff guide wire, positioned across the p
arietal pericardium, and manually inflated until the waisting disappea
red, Echocardiographic study and chest radiograph were taken before, i
mmediately after the procedure, and during follow-up. The procedure wa
s successful and well tolerated in all patients. There were no immedia
te or late complications. No patients developed recurrence of pericard
ial effusion at up to 10 months' follow-up. In conclusion, BP can be p
erformed in patients with MPT with high rate of procedural success. It
may become the preferred treatment to avoid a more invasive procedure
in these critically ill patients.