CLONING AND SEQUENCE-ANALYSIS OF THE CORYNEBACTERIUM-DIPHTHERIAE DTXRHOMOLOG FROM STREPTOMYCES-LIVIDANS AND S-PILOSUS ENCODING A PUTATIVE IRON REPRESSOR PROTEIN

Citation
K. Gunterseeboth et T. Schupp, CLONING AND SEQUENCE-ANALYSIS OF THE CORYNEBACTERIUM-DIPHTHERIAE DTXRHOMOLOG FROM STREPTOMYCES-LIVIDANS AND S-PILOSUS ENCODING A PUTATIVE IRON REPRESSOR PROTEIN, Gene, 166(1), 1995, pp. 117-119
Citations number
16
Categorie Soggetti
Genetics & Heredity
Journal title
GeneACNP
ISSN journal
03781119
Volume
166
Issue
1
Year of publication
1995
Pages
117 - 119
Database
ISI
SICI code
0378-1119(1995)166:1<117:CASOTC>2.0.ZU;2-B
Abstract
The iron-regulated promoter involved in desferrioxamine B synthesis of Streptomyces pilosus contains a region homologous to the iron repress or (DtxR)-binding site of the diphtheria toxin gene promoter in Coryne bacterium diphtheriae [Gunter et al., J. Bacteriol. 175 (1993) 3295-33 02]. Here, we report the cloning and sequencing of the putative Strept omyces iron repressor gene, homologous to dtxR of C. diphtheriae. The N-terminal 139 amino acids of the deduced protein are 73% identical to DtxR.