SURVIVAL OF COMPOSITE CHONDROCUTANEOUS GRAFTS BY VESSEL IMPLANTATION - A STUDY IN THE RABBIT EAR MODEL

Citation
Rl. Arden et al., SURVIVAL OF COMPOSITE CHONDROCUTANEOUS GRAFTS BY VESSEL IMPLANTATION - A STUDY IN THE RABBIT EAR MODEL, The Laryngoscope, 105(12), 1995, pp. 1326-1333
Citations number
52
Categorie Soggetti
Otorhinolaryngology,"Instument & Instrumentation
Journal title
ISSN journal
0023852X
Volume
105
Issue
12
Year of publication
1995
Part
1
Pages
1326 - 1333
Database
ISI
SICI code
0023-852X(1995)105:12<1326:SOCCGB>2.0.ZU;2-U
Abstract
Composite chondrocutaneous graft reconstruction or reattachment has li mited applicability, is traditionally restricted to small segmental lo sses, and is dependent on the status of the recipient bed and graft pe riphery for successful revascularization, Surgical enhancement of comp osite graft survival was experimentally investigated in the rabbit ear model through transposition and appositional placement of an adjacent vascular pedicle. Fluorescein-derived surface-survival determinations , microangiographic vessel-counting methods, and histologic analysis w ere used to study the effects of vascular augmentation, pedicle design variations, and angiogenic substance in sixty 8-cm(2), full-thickness auricular grafts. A statistically significant survival advantage was demonstrated for the implanted grafts, without derived benefit from an giogenic substance, secondary to perivascular angiogenesis from the im planted pedicle.