K. Chijiiwa et al., DIFFERENCES IN GALLBLADDER BILE LITHOGENICITY IN PATIENTS AFTER GASTRECTOMY AND COLECTOMY, European surgical research, 28(1), 1996, pp. 1-7
The differences in lithogenicity of gallbladder bile, biliary lipid co
mposition, cholesterol saturation index (CSI), cholesterol nucleation
time (NT), bilirubin, and ionized calcium were compared in patients wh
o had previously undergone gastrectomy or colectomy. The increased CSI
and the rapid NT were absent in gastrectomized patients, while colect
omy significantly increased the CSI and accelerated the NT. The levels
of ionized calcium and unconjugated bilirubin, possibly responsible f
or pigment stone formation, were significantly higher in patients afte
r gastrectomy, but were nearly absent in patients after colectomy. The
results suggest that after gastrectomy the gallbladder bile indicates
a trend towards pigment stone formation, whereas there is a trend tow
ards cholesterol gallstones after colectomy. The different alterations
of the gallbladder bile lithogenicity are clinically important.