Js. Masin et al., OTITIS-MEDIA FOLLOWING TYMPANOSTOMY TUBE PLACEMENT IN CHILDREN WITH IGG(2) DEFICIENCY, The Laryngoscope, 105(11), 1995, pp. 1188-1190
Children with IgG, deficiency commonly develop recurrent acute otitis
media, It is believed that these infections are secondary to impaired
antibody response rather than eustachian tube dysfunction and are ther
efore less responsive to treatment with tympanostomy tubes. The author
s compared the incidence of acute otitis media in IgG(2)-deficient pat
ients following tympanostomy tube placement with controls in a retrosp
ective cohort study, The charts of 20 patients (10 with IgG(2) deficie
ncy and 10 controls) were reviewed. Episodes of otitis media were reco
rded for 12 months, IgG(2)-deficient patients experienced three times
as many occurrences of otitis media as did controls, This suggests tha
t otitis media is much more common in these patients following tympano
stomy tube placement, We believe that an immunodeficiency work-up shou
ld be considered in patients with multiple episodes of otitis media fo
llowing placement of tympanostomy tubes.