STEREOCONTROLLED FUNCTIONALIZATION AT THE C-9 OF RETINAL - STEREOSELECTIVE SYNTHESIS OF 9-TRANS-9-FLUORORETINAL

Authors
SHINADA T SEKIYA N BOJKOVA N YOSHIHARA K
Citation
T. Shinada et al., STEREOCONTROLLED FUNCTIONALIZATION AT THE C-9 OF RETINAL - STEREOSELECTIVE SYNTHESIS OF 9-TRANS-9-FLUORORETINAL, Synlett, (12), 1995, pp. 1247
Citations number
32
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
12
Year of publication
1995
Database
ISI
SICI code
0936-5214(1995):12<1247:SFATCO>2.0.ZU;2-O
Abstract
A general functionalization at the C-9 of retinal with 9-trans-selecti vity is described. A palladium-catalyzed cross-coupling reaction of 6 and 7 afforded 6E-8, which was elaborated to 9-trans-9-fluororetinal v ia the stereo- and regioselective isomerization.