REPLICATION SLIPPAGE IN THE EVOLUTION OF POTYVIRUSES

Citation
Jm. Hancock et al., REPLICATION SLIPPAGE IN THE EVOLUTION OF POTYVIRUSES, Journal of General Virology, 76, 1995, pp. 3229-3232
Citations number
18
Categorie Soggetti
Virology,"Biothechnology & Applied Migrobiology
Journal title
ISSN journal
00221317
Volume
76
Year of publication
1995
Part
12
Pages
3229 - 3232
Database
ISI
SICI code
0022-1317(1995)76:<3229:RSITEO>2.0.ZU;2-2
Abstract
Recently published evidence for sequence repetition in polyvirus genom es prompted us to analyse the published complete genome sequences and coat protein gene sequences of viruses of this family for evidence of replication slippage. Five of nine complete genomic sequences and 17 o f 32 coat protein genes had significant sequence repetitions. Most of these were in coat protein genes, although the 5' region of the turnip mosaic virus genome also showed evidence of slippage. The results sug gest that replication slippage may be involved in the evolution of vir uses, as well as prokaryotes and eukaryotes, and that slippage can occ ur in both RNA and DNA when it is being replicated.