In this editorial the author examines briefly the past, present and fu
ture of clinical investigation in general and particularly in Switzerl
and, where the same problems are encountered as in other European coun
tries and North America. The main problems reside in the fragmentation
of internal medicine into subspecialties with their own separate meet
ings and journals, at the expense of multidisciplinary sources of info
rmation on medical progress, thus widening the gap between the practit
ioners and the scientific community. Through examples, it is pointed o
ut that the progression of medical knowledge follows the path from bas
ic research in biochemistry, cellular biology, animal experiments, cli
nical investigation and finally clinical medicine not unidirectionally
but bidirectionally. Thanks to the Swiss National Science Foundation,
the Medical Schools of the five Universities and many private foundat
ions, a considerable effort has been made in past decades to foster ba
sic and clinical research, resulting in a most favorable position for
our country on the international scene. There is a fear that political
and administrative decision could jeopardize the present situation an
d imperil the future. Finally, citing Osler from his work ''Aequanimit
as'', the author stresses that ''the true test of a nation's life... i
s to be found in its intellectual and moral standards'', and that ''th
e measure of the value of a nation to the world is neither the bushel
nor the barrel, but mind''.