TRYPANOZOON - INFECTIVITY TO HUMANS IS LINKED TO REDUCED TRANSMISSIBILITY IN TSETSE .1. COMPARISON OF HUMAN SERUM-RESISTANT AND HUMAN SERUM-SENSITIVE FIELD ISOLATES
Sc. Welburn et al., TRYPANOZOON - INFECTIVITY TO HUMANS IS LINKED TO REDUCED TRANSMISSIBILITY IN TSETSE .1. COMPARISON OF HUMAN SERUM-RESISTANT AND HUMAN SERUM-SENSITIVE FIELD ISOLATES, Experimental parasitology, 81(3), 1995, pp. 404-408
The transmissibility of recent isolates of human serum-sensitive (HSS)
and human serum-resistant (HSR) Trypanozoon was compared by transmiss
ion of 37 stocks through an inbred line of Glossina m. morsitans. As i
n previous studies maturation was found to be dependent on fly sex wit
h males producing significantly greater proportions of salivary gland
infections than females. HSS stocks were, however, 1.8 times more like
ly to mature to mammalian infective form than HSR stocks in male tsets
e and 2.7 rimes more likely to mature than HSR stocks in female tsetse
. Infectivity to man has apparently evolved at the expense of transmis
sibility in tsetse, The likelihood of sexual processes occurring in Tr
ypanosoma b. rhodesiense in wild flies is discussed. (C) 1995 Academic
Press, Inc.